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Nick M Clayton Selected Research

1- (4- (3- chlorophenylamino)- 1- methyl- 1H- pyrrolo(3,2- c)pyridin- 7- yl)- 1- morpholin- 4- ylmethanone

10/2009Discovery of 1-[4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a brain penetrant 5-azaindole CB2 agonist for the treatment of chronic pain.

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Nick M Clayton Research Topics

Disease

6Neuralgia (Stump Neuralgia)
08/2010 - 01/2006
6Pain (Aches)
04/2008 - 12/2005
3Hypersensitivity (Allergy)
08/2009 - 12/2005
2Ganglion Cysts (Ganglion)
08/2008 - 02/2007
2Hyperalgesia
07/2008 - 12/2005
1Acute Pain
10/2009
1Chronic Pain
10/2009
1Inflammation (Inflammations)
04/2008
1Lingual Nerve Injuries
02/2007
1Neuroma
01/2007
1Trigeminal Nerve Injuries
11/2006

Drug/Important Bio-Agent (IBA)

2methanesulfonate salt 2-hydroxy-4,4'-diamidinostilbeneIBA
08/2008 - 02/2007
2Analgesics (Analgesic Drugs)IBA
04/2008 - 01/2006
2CB2 Cannabinoid ReceptorIBA
05/2007 - 12/2005
2TRPV Cation ChannelsIBA
02/2007 - 01/2007
1LigandsIBA
08/2010
11- (4- (3- chlorophenylamino)- 1- methyl- 1H- pyrrolo(3,2- c)pyridin- 7- yl)- 1- morpholin- 4- ylmethanoneIBA
10/2009
15-azaindoleIBA
10/2009
16-azaindoleIBA
10/2009
1pyrimidineIBA
08/2009
1Ether (Diethyl Ether)IBA
08/2009
1Purinergic P2 Receptors (ADP Receptor)IBA
08/2008
1Freund's AdjuvantIBA
07/2008
1Cholinergic ReceptorsIBA
07/2008
1Ibuprofen (Motrin)FDA LinkGeneric
04/2008
1PyransIBA
05/2007
1Sodium Channels (Sodium Channel)IBA
11/2006
1Protein Isoforms (Isoforms)IBA
01/2006
1Nitric Oxide Synthase (NO Synthase)IBA
01/2006
1GW 274150IBA
01/2006
1Cannabinoid Receptor AgonistsIBA
12/2005
1HU 211 (HU 210)IBA
12/2005
1CannabinoidsIBA
12/2005
1CarrageenanIBA
12/2005
11,1-dimethylbutyl-1-deoxy-Delta(9)-THCIBA
12/2005